Juan J Marugan Selected Research

Histamine Antagonists (Antihistamines)

4/2015

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.

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Juan J Marugan Research Topics

Disease

6	Infections 01/2018 - 08/2012
5	Neoplasms (Cancer) 01/2022 - 05/2006
5	Lysosomal Storage Diseases (Lysosomal Storage Disease) 12/2016 - 05/2010
4	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 05/2017 - 11/2012
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 09/2014
3	Heart Failure 01/2017 - 01/2013
3	Myotonic Dystrophy (Dystrophia Myotonica) 06/2014 - 02/2012
3	Gaucher Disease (Gaucher's Disease) 06/2012 - 02/2011
2	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022 - 09/2011
2	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2013
2	Type A Niemann-Pick Disease 12/2016 - 11/2012
2	Glycogen Storage Disease Type II (Pompe's Disease) 09/2012 - 05/2010
1	Mucopolysaccharidosis II (Hunter Syndrome) 01/2022
1	Rare Diseases (Rare Disease) 01/2021
1	Galactosemias (Galactosemia) 01/2021
1	Ureteral Obstruction 01/2021
1	Epilepsy (Aura) 01/2020
1	Melanoma (Melanoma, Malignant) 01/2020
1	Liver Cirrhosis (Hepatic Cirrhosis) 11/2019
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 10/2018
1	Tay-Sachs Disease 01/2018
1	Parkinson Disease (Parkinson's Disease) 01/2016
1	Animal Disease Models 01/2016
1	Synucleinopathies 01/2016
1	Hepatitis C 04/2015
1	Hypersensitivity (Allergy) 04/2015
1	Ataxia Telangiectasia (Louis Bar Syndrome) 12/2014
1	Giardiasis 12/2014
1	Microsporidiosis 12/2014
1	Fibrous Dysplasia of Bone 01/2014
1	Polyostotic Fibrous Dysplasia (McCune Albright Syndrome) 01/2014
1	Breast Neoplasms (Breast Cancer) 01/2013
1	Mucopolysaccharidosis III (Sanfilippo Syndrome) 11/2012
1	2 Neuronal Ceroid Lipofuscinosis 11/2012
1	Wolman Disease (Wolman's Disease) 11/2012
1	Inflammation (Inflammations) 08/2012
1	Obesity 08/2012
1	Atherosclerosis 08/2012
1	Muscular Dystrophies (Muscular Dystrophy) 02/2012

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2006
6	EnzymesIBA 01/2021 - 05/2010
5	Pharmaceutical PreparationsIBA 01/2018 - 01/2012
4	Lysergic Acid Diethylamide (LSD)IBA 09/2012 - 05/2010
3	relaxin receptorsIBA 01/2021 - 01/2017
3	RelaxinIBA 11/2019 - 01/2013
3	Therapeutic UsesIBA 11/2019 - 01/2015
3	chlorcyclizineIBA 01/2018 - 04/2015
3	LipidsIBA 01/2018 - 11/2012
3	CholesterolIBA 05/2017 - 11/2012
3	AcidsIBA 12/2016 - 05/2010
2	Peptides (Polypeptides)IBA 11/2019 - 01/2015
2	CyclodextrinsIBA 01/2018 - 05/2017
2	Tocopherols (Tocopherol)IBA 01/2018 - 11/2012
2	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 12/2016 - 08/2012
2	RNA (Ribonucleic Acid)IBA 06/2014 - 02/2012
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2012 - 02/2011
1	pyrrolopyrimidineIBA 01/2022
1	GalactokinaseIBA 01/2021
1	Phosphates (Orthophosphate)IBA 01/2021
1	AntigensIBA 01/2020
1	ConvulsantsIBA 01/2020
1	Hexosaminidase A (Hex A)IBA 01/2018
1	Hexosaminidases (Hexosaminidase)IBA 01/2018
1	Molecular Probes (Molecular Probe)IBA 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2016
1	SynucleinsIBA 01/2016
1	EmetineIBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 06/2015
1	InterferonsIBA 04/2015
1	telaprevirIBA 04/2015
1	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 04/2015
1	daclatasvirIBA 04/2015
1	SofosbuvirIBA 04/2015
1	Antiviral Agents (Antivirals)IBA 04/2015
1	Nonprescription Drugs (Patent Medicines)IBA 04/2015
1	Histamine Antagonists (Antihistamines)IBA 04/2015
1	Ribavirin (Virazole)FDA LinkGeneric 04/2015
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2015
1	Phosphotransferases (Kinase)IBA 12/2014
1	Ataxia Telangiectasia Mutated ProteinsIBA 12/2014
1	Metronidazole (Metric)FDA LinkGeneric 12/2014
1	tioxidazoleIBA 12/2014
1	fumagillinIBA 12/2014
1	CarbadoxIBA 12/2014
1	GTP-Binding Proteins (G-Protein)IBA 01/2014
1	RNA Precursors (Precursor, mRNA)IBA 01/2013
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2013
1	Peptide Hormones (Polypeptide Hormones)IBA 01/2013
1	Sterol Esterase (Hormone-Sensitive Lipase)IBA 11/2012
1	lysosomal proteinsIBA 11/2012
1	GlucosidasesIBA 09/2012
1	CeramidesIBA 08/2012
1	Molecular Chaperones (Chaperone, Molecular)IBA 06/2012
1	Myotonin-Protein KinaseIBA 02/2012
1	3' Untranslated Regions (3' UTR)IBA 02/2012
1	Enzyme ActivatorsIBA 01/2012
1	Glucosylceramides (Glucocerebrosides)IBA 01/2012

Therapy/Procedure

10	Therapeutics 01/2022 - 04/2011
4	Enzyme Replacement Therapy 01/2018 - 01/2012
1	Immunotherapy 01/2020